The quinolones antibiotics - bactericidal drugs
The quinolones are a family of broad-spectrum antibiotics. Quinolones and fluoroquinolones are bactericidal drugs, actively killing bacteria. Quinolones inhibit the bacterial DNA gyrase or the topoisomerase IV enzyme, thereby inhibiting DNA replication and transcription.
The quinolones have been widely used in agriculture and several agents exist which have veterinary but not human use.
For veterinary use:
- danofloxacin (Advocin, Advocid)
- difloxacin (Dicural, Vetequinon)
- enrofloxacin (Baytril)
- ibafloxacin (Ibaflin)
- marbofloxacin (Marbocyl, Zenequin)
- orbifloxacin (Orbax, Victas)
- sarafloxacin (Floxasol, Saraflox, Sarafin)
Resistance to quinolones can develop rapidly, even during a course of treatment.
